Haematology Solutions

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Dr. Rahul Bhargava
M.B.B.S, M. D, DM, Post D.M Fellowship

Dr. Rahul Bhargava is one of the best bone marrow transplant specialist of this generation. Dr Bhargava’ results in the field of adult bone marrow transplant and hematology have been some of the best. Dr Rahul Bhargava is currently the head of hematology and bone marrow transplant at Artemis Hospital, Gurgaon, India. Before Artemis Dr Rahul Bhargava has been associated with Medanta Medicity, Gurgaon, India as bone marrow transplant specialist. Till date, Dr Rahul has done close to 100 adult bone marrow transplants which is record-breaking in whole of North India. dr Rahul Bhargava has also worked in Vancouver, Canada where he specifically trained in Voluntary Stem cell transplant and Umbilical cord transplant. Dr Bhargava’s education has been from one of the best Medical Institutions in India, All India Institute of Medical Sciences (AIIMS), New Delhi, India, The department has its own bone marrow transplantation unit and exhaustive laboratory facilities, providing one of the best yet affordable transplant and other hematological services to not only Indian population but also to people from abroad like Pakistan, Bangladesh, Nepal, Bhutan, Africa, Iraq, Russia and others.

Haematology In Brief

Haematology Solutions functions as a comprehensive referral centre for diagnosis and treatment of haematological related disorders and the management and treatment of all forms of haematological conditions and malignancies.

we offer relief and hope to children and adults with common but dreadful diseases like leukaemia, lymphoma, myeloma and other blood abnormalities. This includes the use of Bone Marrow Transplantation as a curative procedure for many blood cancers and chronic blood diseases where appropriate

Driven by a legacy of advancing haematology innovation, we focus on the science and analytics that create true workflow efficiency and deliver better quality results. Through this scientific leadership, we provide more comprehensive and better patient care

Haematology Solutions are backed by unparalleled service and support to ensure maximum uptime. We provide more cellular analysis solutions that increase productivity while ensuring accuracy and quality of results.

PROJECT GOALS

  • We will provide end to end services in five domains that includes but not limited to Health Tourism, Information Technology, Training, Pharmacy and Infrastructure.
  • The idea is to integrate these disparate services and create a unique platform which will cater to all the needs of the clients.
  • Haematology Solutions will be a facilitator, service provider to the demands/needs of the customer.

Deliverables

 Target a specific area in the domain

Quantify or at least suggest an indicator of progress

Specify who will do it.

State what results can realistically be achieved, given available resources.

Stick to timelines

Keys of Success

  • Professional quality and high standards of services offered.
  • Reliability-being 24/7 availability through on-call, and adequate staffing.
  • Effective collaboration with other community professionals (physicians, nurses, social workers, pharmacists, hospitals, and other organizations)

Scope of Haematology

  • Blood transfusion
  • Coagulation
  • Clinical Hematology
  • Laboratory Hematology
  • Bone Marrow Transplant
  • PICC line insertion
  • Electrolyte infusion/antibiotic infusion
  • Neutropenic care in low infection risk environment
  • Bone Marrow Aspiration and trephine biopsy
  • Lymph node histopathology
  • Red cells disorder
  • Hematological malignancies
  • Acute leukemias
  • Plasma cell disorder
  • Lymphomas
  • Congenital disorders of coagulation
  • Thrombophilia
  • Platelet disorders

Transplant services

Bone Marrow Transplant

PATHOLOGY

  • Treat Leukemia by chemotherapy
  • Regeneration of normal marrow
  • Chemotherapy alone cannot eliminate all malignant cells
  • Stem cell transplants.

TRANSPLANT

  • Patient’s bone marrow stem cells are replaced with healthy cells
  • Existing bone marrow and abnormal leukocytes killed
  • Chemotherapy and radiation
  • Next bone marrow containing healthy stem cells re-infused

PROCEDURE

  • Bone Marrow versus Peripheral Stem Cells
  • Cost
  • Sample size
  • Donor/Patient factors
  • Expertise

Adult Stem Cell Transplant

Adult Stem Cell Transplant

PROCEDURE

  • Most blood stem cells reside in the bone marrow and a small number are present in the bloodstream
  • Multipotent peripheral blood stem cells
  • Can be obtained from drawn blood
  • PBSCs are easier to collect than bone marrow stem cells

HARVESTING

FUNCTION OF BMT UNIT

Handling services & Intensive care for:

  • Mobilization / stem cell collection & infusion.
  • Chemotherapy for pre – transplant
  • Pre & post care for Transplant patients.

TRANSPLANTATION

  • Autologous
  • Allogeneic
  • Syngeneic

INDICATIONS

  • Hematological diseases
    Benign :Thallassaemia, Aplastic Anaemia
    Malignant : Leukemia Lymphoma Myeloma
  • Immune deficiency disorders Pediatric and Adult
  • Neurological Disease (MS)
AUTO TRANSPLANT
ALLOTRANSPLANT

Graft Verses Host Disease (GVHD)

  • GVHD sometimes occurs with allogeneic transplantation.
  • Lymphocytes from the donor graft attack the cells of the host
  • GVHD can usually be treated with steroids or other immunosuppressive agents.
  • Acute GVHD occurs before day 100 post-transplant
  • Chronic GVHD occurs beyond day 100
  • Recent advances have reduced the incidence and severity of this post-transplant complication, but GVHD, directly or indirectly, still accounts for approximately 15% of deaths in stem cell transplant patients
  • Chronic GVHD can develop months or even years post-transplant

SPECIFICITY IN BMT

  • Well equipped Unit
  • Expertise
  • Facility
  • Isolation
  • Phoresis
  • Platelet and blood support
  • Motivated patient

BMT precautions

  • HEPA filtered and positive pressure rooms
  • Appropriate isolation restrictions
  • Hand hygiene
  • Oral care
  • Gut prophylaxis
  • Low bacteria diet
  • No rectal
  • Instrumentations
  • Fever is treated